Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557043 | 0.91 | CHEK2 (0.38) | CHEK2SCN9ANAMPTPDE4BNR1H2 | |
| SCHEMBL28556407 | 0.87 | MAPT (0.36) | CHEK2SCN9AJAK3NAMPTPDE4B | |
| SCHEMBL22857826 | 0.86 | SCN9A (0.42) | CHEK2SCN9APDE4BGPR119USP30 | |
| SCHEMBL28560849 | 0.82 | PDE4D (0.35) | NAMPTPDE4BNR1H2GPR119USP30 | |
| SCHEMBL21158729 | 0.81 | TSHR (0.35) | — | |
| SCHEMBL22857887 | 0.79 | STING1 (0.42) | SCN9A | |
| SCHEMBL28548767 | 0.78 | MAPT (0.37) | CHEK2SCN9ANAMPTPDE4BNR1H2 | |
| SCHEMBL22857866 | 0.78 | STING1 (0.46) | — | |
| SCHEMBL22121045 | 0.78 | TSHR (0.43) | — | |
| SCHEMBL22857823 | 0.77 | CA12 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |