Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556407 | 0.92 | MAPT (0.36) | MAPTGAATP53HTTCHEK2 | |
| SCHEMBL28557043 | 0.87 | CHEK2 (0.38) | CHEK2SCN9AGPR119NAMPTRBP4 | |
| SCHEMBL28556408 | 0.85 | MAPT (0.36) | MAPTGAATP53HTTHCAR3 | |
| SCHEMBL28561982 | 0.85 | RBP4 (0.41) | MAPTTP53HTTCHEK2SCN9A | |
| SCHEMBL28548642 | 0.84 | MAPT (0.45) | MAPTGAATP53HTTHCAR3 | |
| SCHEMBL28548656 | 0.82 | MAPT (0.42) | MAPTGAATP53HTTHCAR3 | |
| SCHEMBL22857826 | 0.80 | SCN9A (0.42) | CHEK2SCN9APKMGPR119RBP4 | |
| SCHEMBL22857831 | 0.78 | SCN9A (0.41) | CHEK2SCN9APKMGPR119RBP4 | |
| SCHEMBL28560847 | 0.78 | CHEK2 (0.38) | CHEK2SCN9AGPR119NAMPTNR1H2 | |
| SCHEMBL28553322 | 0.77 | KMT2A (0.46) | MAPTGAATP53HTTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |