Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859548 | 1.00 | PPARG (0.61) | PPARGHDAC1HDAC6OPRK1ALDH1A1 | |
| SCHEMBL2849845 | 0.92 | PPARG (0.58) | PPARG | |
| SCHEMBL2847851 | 0.92 | PPARG (0.58) | PPARG | |
| SCHEMBL2847849 | 0.92 | PPARG (0.58) | PPARG | |
| SCHEMBL2849821 | 0.92 | PPARG (0.58) | PPARG | |
| SCHEMBL2853812 | 0.83 | TPH1 (0.49) | HDAC1HDAC6OPRK1 | |
| SCHEMBL6158603 | 0.83 | TPH1 (0.49) | HDAC1HDAC6OPRK1 | |
| SCHEMBL6158635 | 0.83 | CTSS (0.53) | HDAC1HDAC6OPRK1ALDH1A1ATM | |
| SCHEMBL2859545 | 0.82 | PPARG (0.61) | PPARGHDAC1HDAC6ALDH1A1 | |
| SCHEMBL6155344 | 0.79 | PPARG (0.49) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | claimed |