SCHEMBL2856243

SCHEMBL2856243

O=S(=O)(O)c1c(O)c(N=Nc2ccccc2)cc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.57
CYP1A2 P05177 3/20 0.55
HIF1A Q16665 2/20 0.55
CYP3A4 P08684 1/20 0.55
STAT6 P42226 1/20 0.55
SUMO2 P61956 1/20 0.53
SUMO1 P63165 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP2 Q9HC62 1/20 0.53
SENP1 Q9P0U3 1/20 0.53
POLB P06746 1/20 0.49
HPGD P15428 2/20 0.48
APP P05067 2/20 0.48
MAPT P10636 2/20 0.48
SNCA P37840 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
THRB P10828 1/20 0.48
ALOX12 P18054 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11829843 0.89 SUMO2 (0.53) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL26964487 0.88 SENP2 (0.56) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL6355023 0.87 CYP2D6 (0.55) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL11433397 0.82 CYP2D6 (0.59) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL8675478 0.81 MPL (0.64) CYP2D6CYP1A2HIF1ASENP7MAPT
SCHEMBL5267969 0.81 SENP2 (0.50) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL5267972 0.81 SENP2 (0.50) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL23787540 0.80 APP (0.68) CYP2D6CYP1A2HIF1ACYP3A4STAT6
SCHEMBL15120313 0.79 SENP2 (0.72) CYP2D6CYP1A2HIF1ASUMO2SUMO1
SCHEMBL11695732 0.79 SENP2 (0.72) CYP2D6CYP1A2HIF1ASUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1760117-B1 Reactive dyestuff compositions and their use EVERLIGHT USA INC (US) 2010-01-13 EP disclosed