SCHEMBL8675478

SCHEMBL8675478

O=S(=O)(O)c1c(O)c(N=Nc2c(O)ccc3ccccc23)cc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 6/20 0.64
CTRC Q99895 2/20 0.64
CYP1A2 P05177 2/20 0.63
HIF1A Q16665 2/20 0.63
CYP2C9 P11712 1/20 0.63
TSHR P16473 1/20 0.63
PTPRA P18433 1/20 0.63
PTPRB P23467 1/20 0.63
CYP2C19 P33261 1/20 0.63
RAPGEF4 Q8WZA2 1/20 0.63
HSD17B10 Q99714 1/20 0.63
MAPT P10636 4/20 0.57
MAPK1 P28482 3/20 0.57
KMT2A Q03164 3/20 0.57
GAA P10253 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
MEN1 O00255 2/20 0.54
ALDH1A1 P00352 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947347 0.87 MPL (0.63) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL29393603 0.87 MPL (0.63) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL344640 0.87 MPL (0.63) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL9577763 0.85 MPL (0.61) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL8675472 0.85 MPL (0.73) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL9577808 0.85 MPL (0.61) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL29912833 0.85 MPL (0.61) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL9577835 0.85 MPL (0.61) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL9577832 0.85 MPL (0.61) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL18103384 0.84 MPL (0.71) MPLCTRCCYP1A2HIF1ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10337199-A None JP disclosed
JP-H10337199-A NUCLEIC ACID STAIN, DETECTION OF DOUBLE-STRANDED NUCLEIC ACID USING THE SAME AND DETECTION REAGENT FOR TARGETED NUCLEIC ACID UNITIKA LTD 1998-12-22 JP disclosed