Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549632 | 0.91 | MAPT (0.53) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28563175 | 0.89 | LMNA (0.59) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28566132 | 0.85 | MAPT (0.53) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28566162 | 0.83 | MAPT (0.64) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28571382 | 0.82 | LMNA (0.54) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28912936 | 0.79 | MAPT (0.55) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28559692 | 0.77 | LMNA (0.61) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28553690 | 0.77 | CA1 (0.55) | MAPTPOLBLMNAMEN1KMT2A | |
| SCHEMBL28560080 | 0.77 | MAPT (0.64) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL16430875 | 0.72 | MAPT (0.58) | MAPTPOLBL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |