Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571382 | 0.90 | LMNA (0.54) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28563149 | 0.89 | MAPT (0.58) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28559692 | 0.84 | LMNA (0.61) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28912333 | 0.82 | LMNA (0.65) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28549632 | 0.82 | MAPT (0.53) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28566132 | 0.77 | MAPT (0.53) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28554391 | 0.76 | MAPT (0.64) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL11233436 | 0.76 | KMT2A (0.55) | LMNAKDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL24704031 | 0.74 | KDM4E (1.00) | LMNAKDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28558521 | 0.72 | KDM4E (0.72) | LMNAKDM4EMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |