Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573940 | 0.86 | HDAC8 (0.46) | PPARGALDH1A1GALR3RAB9ASMN1; SMN2 | |
| SCHEMBL28566467 | 0.81 | PLAU (0.56) | PPARGRAB9ASMN1; SMN2 | |
| SCHEMBL28565969 | 0.81 | PPARG (0.53) | PPARGRAB9ASMN1; SMN2TSHR | |
| SCHEMBL14121203 | 0.81 | PPARG (0.50) | PPARG | |
| SCHEMBL4201771 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GALR3RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14233800 | 0.79 | PPARG (0.70) | PPARG | |
| SCHEMBL15971036 | 0.79 | PLAU (0.57) | PPARGAPP | |
| SCHEMBL30888879 | 0.79 | PLAU (0.57) | PPARGAPP | |
| SCHEMBL6087730 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GALR3RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28582467 | 0.78 | PPARG (0.52) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-112759541-A | Indole-like derivatives and uses thereof | 复旦大学 | 2021-05-07 | — | — | CN | disclosed |