SCHEMBL2856342

SCHEMBL2856342

C[Si](C)(C)C#Cc1cccc(-c2ccccc2)c1C#C[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 3/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
GRM5 P41594 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.34
CREBBP Q92793 1/20 0.33
FFAR1 O14842 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21097451 0.85 GRM5 (0.49) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL20791596 0.83 MAPT (0.40) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL21451361 0.83 PDCD1 (0.43) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL5354381 0.81 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL29865535 0.81 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL28815370 0.81 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL5349142 0.81 HPGD (0.47) ALDH1A1HSD17B10HPGDTSHRMEN1
SCHEMBL3845195 0.81 KDM4E (0.41) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL10535351 0.77 TSHR (0.45) ALDH1A1HSD17B10HPGDKDM4ETSHR
SCHEMBL3839029 0.74 KDM4E (0.49) ALDH1A1HSD17B10HPGDKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1768466-B1 Organic luminous material and organic light-emitting device FUJITSU LTD (JP) 2010-01-20 EP disclosed
EP-1768465-A2 Organic luminous material and organic light-emitting device Fujitsu Ltd. (JP) 2007-03-28 EP disclosed
EP-1768466-A2 Organic luminous material and organic light-emitting device FUJITSU LIMITED (JP) 2007-03-28 EP disclosed
EP-1760799-A2 Organic luminous material and organic light-emitting device Fujitsu Ltd. (JP) 2007-03-07 EP disclosed
EP-1741765-A2 Organic luminous material and organic light-emitting device FUJITSU LIMITED (JP) 2007-01-10 EP disclosed
US-6846580-B2 Organic luminous material and organic light-emitting device FUJITSU LIMITED (JP) 2005-01-25 US disclosed
US-20040155577-A1 Organic luminous material and organic light-emitting device FUJITSU LIMITED (JP) 2004-08-12 US disclosed
US-20020001734-A1 Organic luminous material and organic light-emitting device FUJITSU LIMITED (JP) 2002-01-03 US disclosed
EP-1158839-A2 Organic luminous material and organic light-emitting device FUJITSU LIMITED (JP) 2001-11-28 EP disclosed
US-4814472-A Diethynylated diphenyl hexafluoropropanes HUGHES AIRCRAFT COMPANY (US) 1989-03-21 US disclosed
US-4374291-A Synthesis of bis(ethynylphenyl) compounds HUGHES AIRCRAFT COMPANY (US) 1983-02-15 US disclosed