Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856342 | 0.81 | ALDH1A1 (0.40) | HPGDALDH1A1BCL2L1HSD17B10SMN1; SMN2 | |
| SCHEMBL5354381 | 0.77 | ALDH1A1 (0.42) | HPGDALDH1A1BCL2L1HSD17B10BACE1 | |
| SCHEMBL5345949 | 0.73 | ALOX5 (0.47) | HPGDALDH1A1BCL2L1HSD17B10BACE1 | |
| SCHEMBL21097451 | 0.73 | GRM5 (0.49) | HPGDALDH1A1BCL2L1HSD17B10SMN1; SMN2 | |
| SCHEMBL7789365 | 0.73 | ALDH1A1 (0.56) | HPGDALDH1A1BCL2L1HSD17B10BACE1 | |
| SCHEMBL38652648 | 0.73 | ALDH1A1 (0.56) | HPGDALDH1A1BCL2L1HSD17B10BACE1 | |
| SCHEMBL5139920 | 0.73 | ALDH1A1 (0.56) | HPGDALDH1A1BCL2L1HSD17B10BACE1 | |
| 2-Phenylphenol SCHEMBL8986460 | 0.71 | HPGD (0.90) | HPGDALDH1A1BCL2L1HSD17B10BACE1 | |
| SCHEMBL21451361 | 0.71 | PDCD1 (0.43) | HPGDALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL20791596 | 0.71 | MAPT (0.40) | HPGDALDH1A1HSD17B10MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291692-B2 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050096452-A1 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |