Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 4/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | LATS1 | O95835 | 2/20 | 0.47 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577780 | 0.98 | AOC1 (0.61) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL7088289 | 0.93 | AOC1 (0.58) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL13742816 | 0.85 | AOC1 (0.48) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL21093546 | 0.84 | KDM4E (0.59) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL16054255 | 0.84 | KDM4E (0.59) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL19851080 | 0.84 | KDM4E (0.59) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL31389919 | 0.79 | AOC1 (0.42) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL29539060 | 0.78 | AOC1 (0.54) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL5958407 | 0.78 | AOC1 (0.54) | AOC1AOC3KDM4EGAAMAPT | |
| SCHEMBL17377190 | 0.77 | AOC1 (0.57) | AOC1AOC3KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |