Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229908 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL12622274 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL12622306 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL6736726 | 0.81 | HSD17B10 (0.55) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL13539888 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL11976539 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL12628223 | 0.77 | HSD11B1 (0.62) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL11927622 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL13549537 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL16615370 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | claimed |
| EP-1753747-B1 | 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-01-13 | — | — | EP | claimed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | claimed |
| EP-1753747-A1 | 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS | Pierre Fabre Dermo-Cosmetique (FR) | 2007-02-21 | — | — | EP | claimed |
| WO-2005121128-A1 | 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2005-12-22 | — | — | WO | claimed |
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | disclosed |
| EP-1753747-B1 | 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-01-13 | — | — | EP | disclosed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | TYR, H1-0, TELO2 | ALDH1A1 785/4885MAPT 4276/4885KDM4E 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.