Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.80 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.76 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | JAK2 | O60674 | 1/20 | 0.70 |
| ▸ | TYK2 | P29597 | 1/20 | 0.70 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Phenylbenzamide SCHEMBL7787063 | 1.00 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| SCHEMBL24202631 | 0.98 | SIRT1 (0.83) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.98 | SIRT1 (0.83) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL31966 | 0.98 | SIRT1 (0.83) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL11337922 | 0.95 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL11334226 | 0.95 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL6718614 | 0.95 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL8372230 | 0.95 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL23248037 | 0.95 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL15955219 | 0.95 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336756-B | Hydrogenation dehalogenation method of halogenated aromatic hydrocarbon | 河南大学 | 2021-05-11 | — | — | CN | disclosed |