Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.83 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.80 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.79 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | JAK2 | O60674 | 1/20 | 0.73 |
| ▸ | TYK2 | P29597 | 1/20 | 0.73 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.70 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Phenylbenzamide SCHEMBL31966 | 1.00 | SIRT1 (0.83) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| SCHEMBL24202631 | 1.00 | SIRT1 (0.83) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL11337922 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL8372230 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL7787063 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL23248037 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL11334226 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL6718614 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL28564307 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 | |
| N-Phenylbenzamide SCHEMBL15955219 | 0.98 | SIRT1 (0.80) | SIRT1PTPN1KCNK3KCNK9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235142-B2 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON (US) | 2007-06-26 | — | — | US | disclosed |
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | SHASUN PHARMA SOLUTIONS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | AOC1, AOC3, NUDT1 | SIRT1 2258/4885PTPN1 4470/4885KCNK3 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.