SCHEMBL28564394

SCHEMBL28564394

COC(=O)/C(F)=C(/F)C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TET2 Q6N021 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
TSHR P16473 3/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAPT P10636 1/20 0.37
HSD17B10 Q99714 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
TGFBR1 P36897 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276154 0.86
SCHEMBL9967802 0.83
SCHEMBL11073269 0.81
SCHEMBL5213613 0.81
SCHEMBL15546439 0.81 ALDH1A1 (0.46) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL25855628 0.81 ALDH1A1 (0.39) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL28877363 0.81
SCHEMBL15546330 0.81 ALDH1A1 (0.46) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL6950834 0.79 ALDH1A1 (0.56) ALDH1A1TET2EGLN1TSHRKEAP1
SCHEMBL8295 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112812305-A Fluorine modified PAE resin, preparation method thereof and coating composition 浙江艾特普科技有限公司 2021-05-18 CN claimed
CN-112812305-A Fluorine modified PAE resin, preparation method thereof and coating composition 浙江艾特普科技有限公司 2021-05-18 CN disclosed