SCHEMBL25855628

SCHEMBL25855628

COC(=O)/C(O)=C(\F)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
EGLN1 Q9GZT9 1/20 0.37
MAPT P10636 1/20 0.32
TGFBR1 P36897 1/20 0.32
TET2 Q6N021 1/20 0.32
HCAR2 Q8TDS4 2/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28564394 0.81 ALDH1A1 (0.47) ALDH1A1EGLN1MAPTTGFBR1TET2
SCHEMBL3185570 0.81 ALDH1A1 (0.47) ALDH1A1EGLN1MAPTTGFBR1TET2
SCHEMBL823296 0.81 ALDH1A1 (0.47) ALDH1A1EGLN1MAPTTGFBR1TET2
SCHEMBL7770999 0.81 ALDH1A1 (0.47) ALDH1A1EGLN1MAPTTGFBR1TET2
SCHEMBL28386374 0.75
SCHEMBL1276154 0.75
SCHEMBL9967802 0.73
SCHEMBL3048415 0.73
SCHEMBL8607826 0.73 ALDH1A1 (0.41) ALDH1A1EGLN1TGFBR1TET2HCAR2
SCHEMBL8605808 0.73 ALDH1A1 (0.41) ALDH1A1EGLN1TGFBR1TET2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234910-A1 PRODUCTION METHOD OF ACRYLIC ACID DERIVATIVE DAIKIN INDUSTRIES, LTD. (JP) 2023-07-27 US disclosed
US-20230234910-A1 PRODUCTION METHOD OF ACRYLIC ACID DERIVATIVE DAIKIN INDUSTRIES, LTD. (JP) 2023-07-27 US disclosed
EP-4212508-A1 PRODUCTION METHOD OF ACRYLIC ACID DERIVATIVE Daikin Industries, Ltd. (JP) 2023-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234910-A1 PRODUCTION METHOD OF ACRYLIC ACID DERIVATIVE ADH1A, ALDH7A1, ALDH3A1 ALDH1A1 4/4885EGLN1 343/4885MAPT 4496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.