Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134693 | 0.79 | ERCC5 (0.56) | KDM4EALDH1A1MAPTPARP1ERCC5 | |
| SCHEMBL29403016 | 0.79 | ERCC5 (0.56) | KDM4EALDH1A1MAPTPARP1ERCC5 | |
| SCHEMBL28561506 | 0.79 | CES2 (0.45) | KDM4EALDH1A1MAPTLMNANPC1 | |
| SCHEMBL27804569 | 0.78 | CYP19A1 (0.44) | KDM4EALDH1A1MAPTKMT2APOLB | |
| SCHEMBL5489563 | 0.75 | HPGD (0.45) | KDM4EALDH1A1MAPTPARP1ERCC5 | |
| SCHEMBL30854357 | 0.73 | MEN1 (0.53) | ALDH1A1PARP1ERCC5FEN1LMNA | |
| SCHEMBL29281177 | 0.73 | MEN1 (0.53) | ALDH1A1PARP1ERCC5FEN1LMNA | |
| SCHEMBL4738159 | 0.72 | PARP1 (0.47) | KDM4EALDH1A1MAPTPARP1ERCC5 | |
| SCHEMBL11818989 | 0.70 | ERCC5 (0.57) | ALDH1A1MAPTPARP1ERCC5FEN1 | |
| SCHEMBL8045032 | 0.70 | ERCC5 (0.53) | KDM4EALDH1A1MAPTPARP1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739350-B | Method for synthesizing 2-aminothiazole derivative | 天津大学 | 2020-12-22 | — | — | CN | disclosed |