Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200753 | 0.81 | PARP1 (0.43) | ALDH1A1POLBMAPTPARP1TP53 | |
| SCHEMBL5777797 | 0.81 | PBRM1 (0.42) | ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL3411071 | 0.80 | BCL2L1 (0.42) | HPGDALDH1A1GAAPOLBMAPT | |
| SCHEMBL5776042 | 0.79 | NOS1 (0.42) | ALDH1A1 | |
| SCHEMBL289811 | 0.79 | EGFR (0.50) | HPGDALDH1A1MAPTHTTMAOA | |
| SCHEMBL26921657 | 0.78 | ERCC5 (0.56) | HPGDALDH1A1GAAPOLBMAPT | |
| SCHEMBL29839155 | 0.78 | ERCC5 (0.56) | HPGDALDH1A1GAAPOLBMAPT | |
| SCHEMBL5771539 | 0.77 | CES2 (0.50) | ALDH1A1POLBTP53 | |
| SCHEMBL1651006 | 0.76 | HCAR2 (0.46) | ALDH1A1PKMKDM4E | |
| SCHEMBL5779568 | 0.76 | BCHE (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009445-A1 | Aerosol compositions and methods | XEMPLAR PHARMACEUTICALS, LLC (US) | 2007-01-11 | — | — | US | disclosed |
| EP-0731688-B1 | AEROSOL DRUG FORMULATIONS FOR USE WITH NON-CFC PROPELLANTS | ABBOTT LAB (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-0777467-B1 | AEROSOL DRUG FORMULATIONS CONTAINING POLYGLYCOLYZED GLYCERIDES | ABBOTT LAB (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6193954-B1 | ADMINISTERING THERAPEUTICALLY EFFECTIVE AMOUNT OF DRUG DOPAMINE AGONIST, A PROPELLANT AND POLOXAME TO PATIENT | ABBOTT LABORATORIES | 2001-02-27 | — | — | US | disclosed |
| EP-0804157-A1 | AEROSOL DRUG FORMULATIONS CONTAINING VITAMIN E | Abbott Laboratories (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0777467-A1 | AEROSOL DRUG FORMULATIONS CONTAINING POLYGLYCOLYZED GLYCERIDES | Abbott Laboratories (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006598-A1 | AEROSOL DRUG FORMULATIONS CONTAINING POLYGLYCOLYZED GLYCERIDES | ABBOTT LABORATORIES (US) | 1996-03-07 | — | — | WO | disclosed |
| WO-1995024892-A1 | AEROSOL DRUG FORMULATIONS CONTAINING VITAMIN E | ABBOTT LABORATORIES (US) | 1995-09-21 | — | — | WO | disclosed |