Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791078 | 0.82 | KDM5B (0.33) | KDM5BFFAR3LCKFYN | |
| SCHEMBL5315913 | 0.78 | CRBN (0.50) | CRBNTAS2R38CA2NFKB1KDM5B | |
| SCHEMBL29356869 | 0.77 | CRBN (0.53) | CRBNTAS2R38KDM4ECA2PTGS1 | |
| SCHEMBL24394998 | 0.74 | MEN1 (0.36) | KDM4EFFAR3 | |
| SCHEMBL2947344 | 0.74 | — | — | |
| SCHEMBL20659186 | 0.73 | — | — | |
| SCHEMBL6038209 | 0.73 | — | — | |
| SCHEMBL15547192 | 0.72 | TRPA1 (0.38) | — | |
| SCHEMBL13599875 | 0.71 | — | — | |
| SCHEMBL24394964 | 0.71 | HDAC3 (0.44) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824421-A | Chiral phosphine-phosphoramidite ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2021-05-21 | — | — | CN | disclosed |