Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 6/20 | 0.71 |
| ▸ | APP | P05067 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CTSC | P53634 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568814 | 0.87 | APP (0.79) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL1391344 | 0.87 | APP (0.79) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL2113984 | 0.85 | AURKA (0.77) | IDH2APPAURKACTSCKDM4E | |
| SCHEMBL2807227 | 0.84 | IDH2 (0.58) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL2831791 | 0.84 | IDH2 (0.56) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL28458402 | 0.83 | IDH2 (0.85) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL30568833 | 0.82 | IDH2 (1.00) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL16540893 | 0.81 | APP (0.51) | IDH2APP | |
| SCHEMBL13771505 | 0.81 | APP (0.76) | IDH2APPMAPTLMNAAURKA | |
| SCHEMBL30568865 | 0.81 | MAPT (0.83) | IDH2APPMAPTLMNAAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |