Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 8/20 | 0.58 |
| ▸ | APP | P05067 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856487 | 0.84 | IDH2 (0.71) | IDH2APPMAPTLMNAMAPK1 | |
| SCHEMBL1391062 | 0.81 | APP (0.65) | IDH2APPMAPTLMNAMAPK1 | |
| SCHEMBL12484581 | 0.80 | STK17A (0.46) | APPMAPTLMNACTSC | |
| SCHEMBL12485617 | 0.79 | IDH2 (0.62) | IDH2MAPTLMNAMAPK1 | |
| SCHEMBL12486143 | 0.78 | CTSS (0.48) | — | |
| SCHEMBL12485625 | 0.77 | USP2 (0.60) | IDH2MAPT | |
| SCHEMBL12483182 | 0.77 | KCNH3 (0.48) | APPMAPTLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL17698146 | 0.77 | USP2 (0.59) | IDH2MAPT | |
| SCHEMBL30568814 | 0.76 | APP (0.79) | IDH2APPMAPTLMNAMAPK1 | |
| SCHEMBL1391344 | 0.76 | APP (0.79) | IDH2APPMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |