4-Methoxycinnamic Acid

4-Methoxycinnamic Acid

SCHEMBL28564901

C=CC(=C)C.COc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.78
ATM Q13315 1/20 0.78
F3 P13726 2/20 0.60
GSK3B P49841 2/20 0.57
BACE1 P56817 1/20 0.56
HDAC3 O15379 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
BCHE P06276 1/20 0.55
CYP3A4 P08684 1/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.54
XDH P47989 1/20 0.54
PTGS2 P35354 1/20 0.52
MAPT P10636 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methoxycinnamic Acid SCHEMBL2468607 0.92 THRB (0.86) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL6578183 0.89 THRB (0.93) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL28265437 0.89 THRB (0.93) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL6578185 0.89 THRB (0.93) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL12473722 0.88 THRB (1.00) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL58699 0.88 THRB (1.00) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL58700 0.88 THRB (1.00) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL10935651 0.87 THRB (0.96) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL2298853 0.87 THRB (0.96) THRBATMF3GSK3BBACE1
4-Methoxycinnamic Acid SCHEMBL8500105 0.87 THRB (0.96) THRBATMF3GSK3BBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113559003-B Sunscreen composition with high UVA protection effect and application thereof 宝萃生物科技有限公司 2022-08-02 CN disclosed
CN-113559003-A Sunscreen composition with high UVA protection effect and application thereof 宝萃生物科技有限公司 2021-10-29 CN disclosed
CN-113230155-A Sprayable cosmetic sunscreen compositions 盖尔德玛公司 2021-08-10 CN disclosed
CN-107249550-B Sunscreen cosmetic compositions 盖尔德玛公司 2021-07-02 CN disclosed
CN-107249557-B Sprayable cosmetic sunscreen compositions 盖尔德玛公司 2021-05-25 CN disclosed
CN-106535874-B Pore reducing agent 玫琳凯有限公司 2021-05-04 CN disclosed
CN-107427452-B Extract obtained from brown algae gametophyte and application of extract as anti-aging active ingredient of cosmetic 化工产品开发公司SEPPIC 2021-04-09 CN disclosed