Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.43 |
| ▸ | LPL | P06858 | 11/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064074 | 0.91 | DGAT1 (0.45) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL23816604 | 0.91 | DGAT1 (0.45) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL2316680 | 0.84 | DGAT1 (0.47) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL22748773 | 0.84 | LPL (0.62) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL23294857 | 0.83 | LPL (0.41) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL6937341 | 0.83 | DGAT1 (0.44) | DGAT1LIPGLPLF11CXCR2 | |
| SCHEMBL2426973 | 0.80 | LPL (0.49) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL29744209 | 0.80 | LPL (0.49) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL2585735 | 0.79 | DGAT1 (0.46) | DGAT1LIPGLPLF11FFAR1 | |
| SCHEMBL31469579 | 0.78 | LPL (0.45) | DGAT1LIPGLPLF11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724134-B | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-113214247-A | Azaindole derivative marrow cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-112724134-A | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-04-30 | — | — | CN | disclosed |