SCHEMBL2856529

SCHEMBL2856529

O=c1oc(Oc2ccccc2)nn1-c1ccc(Br)cc1

nearest known ligand 0.75

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.67
FAAH O00519 1/20 0.67
ABHD16A O95870 1/20 0.47
BCHE P06276 1/20 0.44
LIPC P11150 1/20 0.44
ACHE P22303 1/20 0.44
LIPE Q05469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2855348 0.90 MGLL (0.71) MGLLFAAHABHD16ABCHELIPC
SCHEMBL3458215 0.81 MGLL (0.48) MGLLFAAHBCHELIPCACHE
SCHEMBL6552566 0.80 MGLL (1.00) MGLLFAAHABHD16A
SCHEMBL9553638 0.80 MGLL (0.60) MGLLFAAHBCHELIPCACHE
SCHEMBL2233598 0.79 ABHD16A (0.72) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL2853740 0.77 MGLL (0.66) MGLLFAAHABHD16A
SCHEMBL9553707 0.77 MGLL (0.56) MGLLFAAH
SCHEMBL2701979 0.76 MGLL (0.61) MGLLFAAHBCHELIPCACHE
SCHEMBL2826312 0.76 MGLL (0.55) MGLLFAAHABHD16ABCHELIPC
SCHEMBL6551376 0.72 MGLL (1.00) MGLLFAAHABHD16ABCHELIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2238131-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL - Portela & Ca., S.A. (PT) 2010-10-13 EP disclosed
WO-2009084970-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL-PORTELA & COMPANHIA, S.A. (PT) 2009-07-09 WO disclosed