SCHEMBL2853740

SCHEMBL2853740

COc1cccc(-c2ccc(-n3nc(Oc4ccccc4)oc3=O)cc2)c1

nearest known ligand 0.70

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.66
FAAH O00519 1/20 0.66
DHODH Q02127 1/20 0.50
ABHD16A O95870 1/20 0.48
NPBWR1 P48145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551854 0.82 FAAH (0.74) MGLLFAAHABHD16A
SCHEMBL2855348 0.81 MGLL (0.71) MGLLFAAHABHD16A
SCHEMBL6552566 0.80 MGLL (1.00) MGLLFAAHABHD16A
SCHEMBL6552790 0.79 MGLL (0.74) MGLLFAAHABHD16A
SCHEMBL6551376 0.78 MGLL (1.00) MGLLFAAHABHD16A
SCHEMBL2856529 0.77 MGLL (0.67) MGLLFAAHABHD16A
SCHEMBL2853266 0.75 MGLL (0.64) MGLLFAAHABHD16ANPBWR1
SCHEMBL9553638 0.74 MGLL (0.60) MGLLFAAH
SCHEMBL11620781 0.74 FAAH (0.78) MGLLFAAHABHD16A
SCHEMBL2701979 0.74 MGLL (0.61) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2238131-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL - Portela & Ca., S.A. (PT) 2010-10-13 EP disclosed
WO-2009084970-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL-PORTELA & COMPANHIA, S.A. (PT) 2009-07-09 WO disclosed