Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39664 | 0.76 | HSD11B1 (0.44) | HSD11B1CYP2C9L3MBTL1 | |
| SCHEMBL6657914 | 0.74 | HSD11B1 (0.42) | HSD11B1CYP2C9L3MBTL1 | |
| SCHEMBL6912960 | 0.74 | HSD11B1 (0.42) | HSD11B1CYP2C9L3MBTL1 | |
| SCHEMBL16499883 | 0.73 | — | — | |
| SCHEMBL21425644 | 0.70 | HSD11B1 (0.35) | HSD11B1CYP2C9 | |
| SCHEMBL13909214 | 0.67 | — | — | |
| SCHEMBL14266973 | 0.67 | — | — | |
| SCHEMBL21426648 | 0.67 | HSD11B1 (0.37) | HSD11B1CYP2C9 | |
| SCHEMBL14202660 | 0.67 | HSD11B1 (0.37) | HSD11B1CYP2C9L3MBTL1 | |
| SCHEMBL18506084 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269741-A | Cycloalkyl and heterocycloalkyl inhibitors, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-112694475-A | Cycloalkyl and heterocycloalkyl inhibitors, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2021-04-23 | — | — | CN | disclosed |