SCHEMBL28565352

SCHEMBL28565352

COC(CCNOC(N)=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28118524 0.75 MTNR1A (0.32)
SCHEMBL31277126 0.72 ANPEP (0.37)
SCHEMBL5555218 0.72
SCHEMBL974052 0.69
SCHEMBL28610088 0.68 CHRNB2 (0.53)
SCHEMBL27548897 0.68
SCHEMBL21877077 0.68 CYP2D6 (0.39)
SCHEMBL28025797 0.68 KDM4E (0.46)
SCHEMBL29110385 0.67
SCHEMBL322313 0.67 KMT2A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778330-A Pyridone-containing polycyclic derivative inhibitor, and preparation method and application thereof 上海翰森生物医药科技有限公司 2021-05-11 CN disclosed