Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558437 | 1.00 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22090190 | 0.81 | LMNA (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5200741 | 0.79 | TSHR (0.40) | LMNACHRM2CHRM4CHRM1TSHR | |
| SCHEMBL22501356 | 0.78 | LMNA (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22501355 | 0.78 | LMNA (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29100176 | 0.78 | LMNA (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28336187 | 0.77 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL17204865 | 0.77 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10610112 | 0.74 | KLK7 (0.31) | — | |
| SCHEMBL10570784 | 0.74 | TRPA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679495-B | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113717170-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-109311870-B | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-112745316-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-112679495-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-04-20 | — | — | CN | disclosed |