D-Glutamate

D-Glutamate

SCHEMBL28565442

NC(CCC(=O)O)C(=O)O.NCCc1ccccn1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.57
CYP1A2 P05177 4/20 0.49
GRIN2D O15399 2/20 0.49
GRIN3B O60391 2/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2A Q12879 2/20 0.49
GRIN2B Q13224 2/20 0.49
GRIN2C Q14957 2/20 0.49
GRIN3A Q8TCU5 2/20 0.49
GRM8 O00222 1/20 0.49
GRM6 O15303 1/20 0.49
GSR P00390 1/20 0.49
GRIK1 P39086 1/20 0.49
GRM5 P41594 1/20 0.49
GRIA1 P42261 1/20 0.49
GRIA2 P42262 1/20 0.49
GRIA3 P42263 1/20 0.49
SLC1A3 P43003 1/20 0.49
SLC1A2 P43004 1/20 0.49
SLC1A1 P43005 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL28271789 0.85 CYP1A2 (0.50) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30428132 0.84 SLC1A5 (0.56) HRH1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL1176394 0.84 SLC1A5 (0.56) HRH1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL1768948 0.84 SLC1A5 (0.56) HRH1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL28078250 0.81 CYP1A2 (0.55) HRH1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL28078253 0.81 CYP1A2 (0.55) HRH1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL5076600 0.79 KMT2A (0.52) SMN1; SMN2ALDH1A1LTA4HHPGDALOX15
SCHEMBL5076589 0.79 KMT2A (0.52) SMN1; SMN2ALDH1A1LTA4HHPGDALOX15
SCHEMBL28102642 0.79 HRH1 (0.55) HRH1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL28102643 0.79 HRH1 (0.55) HRH1CYP1A2GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109225172-B Cadmium carbonate adsorbing material in wheat field soil, preparation and application 长安大学 2021-05-18 CN claimed
CN-109225172-B Cadmium carbonate adsorbing material in wheat field soil, preparation and application 长安大学 2021-05-18 CN disclosed