Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.56 |
| ▸ | PTPRA | P18433 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428132 | 1.00 | SLC1A5 (0.56) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL1176394 | 1.00 | SLC1A5 (0.56) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL28078250 | 0.90 | CYP1A2 (0.55) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL28078253 | 0.90 | CYP1A2 (0.55) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL28102642 | 0.88 | HRH1 (0.55) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL28102643 | 0.88 | HRH1 (0.55) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL14795518 | 0.87 | HRH1 (0.50) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL7075416 | 0.84 | PTPRA (0.59) | PTPRACYP1A2HRH1SMN1; SMN2CYP2C19 | |
| D-Glutamate SCHEMBL28565442 | 0.84 | HRH1 (0.57) | SLC1A5PTPRACYP1A2HRH1SMN1; SMN2 | |
| SCHEMBL126508 | 0.83 | PTPRA (0.67) | SLC1A5PTPRACYP1A2SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| CN-115093463-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3201218-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| CN-105324390-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| CN-105849119-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-01-19 | — | — | CN | disclosed |
| EP-3280723-B1 | BACKBONE-CYCLIZED PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-01-06 | — | — | EP | disclosed |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2020-11-10 | — | — | US | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2014-09-25 | — | — | US | disclosed |
| EP-2764010-A1 | TEMPLATE -FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | Polyphor Ag (CH) | 2014-08-13 | — | — | EP | disclosed |
| US-8754038-B2 | Template-fixed peptidomimetics with CCR10 antagonistic activity | POLYPHOR AG (CH) | 2014-06-17 | — | — | US | disclosed |
| WO-2013050346-A1 | TEMPLATE -FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2012-11-08 | — | — | US | disclosed |
| CN-102712676-A | Template-fixed peptidomimetics with CCR10 antagonistic activty | POLYPHOR AG | 2012-10-03 | — | — | CN | disclosed |
| EP-2501715-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | Polyphor Ag (CH) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060937-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | FPR1, FPR3, FPR2 | SLC1A5 2090/4885PTPRA 1889/4885CYP1A2 3696/4885 |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | CCR10, CCR1, CCRL2 | SLC1A5 1793/4885PTPRA 1991/4885CYP1A2 4368/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | SLC1A5 3359/4885PTPRA 2521/4885CYP1A2 4776/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | SLC1A5 3568/4885PTPRA 2822/4885CYP1A2 4541/4885 |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLQ, POLL, POLM | SLC1A5 3032/4885PTPRA 2526/4885CYP1A2 4770/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | SLC1A5 4220/4885PTPRA 3196/4885CYP1A2 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.