Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CBR1 | P16152 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542862 | 0.82 | PNLIP (0.43) | PNLIPSLC6A2SLC6A3ARSCN8A | |
| SCHEMBL12096571 | 0.80 | AR (0.45) | SLC6A2SLC6A3MAPTNR1I2LMNA | |
| SCHEMBL9589145 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A3MAPTARSLC6A4 | |
| SCHEMBL9589491 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A3MAPTARSLC6A4 | |
| SCHEMBL7809458 | 0.79 | TTR (0.47) | SLC6A2SLC6A3MAPTNR1I2LMNA | |
| SCHEMBL9588248 | 0.79 | AR (0.48) | SLC6A2SLC6A3MAPTARSLC6A4 | |
| SCHEMBL9588339 | 0.78 | AR (0.50) | SLC6A2SLC6A3MAPTTTRAR | |
| SCHEMBL9589204 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A3MAPTARSLC6A4 | |
| SCHEMBL9588170 | 0.78 | AR (0.50) | SLC6A2SLC6A3MAPTARSLC6A4 | |
| SCHEMBL10825618 | 0.77 | MRGPRX4 (0.48) | PNLIPMRGPRX4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689633-A | For inhibiting Nav1.8 pyridine carboxamide Compounds | 利伯研究所公司 | 2021-04-20 | — | — | CN | disclosed |