Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572004 | 0.86 | TRPV1 (0.46) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL30566316 | 0.86 | TRPV1 (0.46) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28557139 | 0.84 | UTS2R (0.46) | MAPTALDH1A1POLBHTTNPSR1 | |
| SCHEMBL28557135 | 0.84 | KDM4E (0.47) | POLBALOX15KDM4E | |
| SCHEMBL28571353 | 0.84 | CYP19A1 (0.51) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL30566314 | 0.84 | CYP19A1 (0.51) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28569096 | 0.76 | AURKA (0.47) | MAPTSMN1; SMN2ALDH1A1NPC1POLB | |
| SCHEMBL28574449 | 0.76 | NAMPT (0.46) | MAPTNPC1RAB9AKDM4ELMNA | |
| SCHEMBL4167921 | 0.74 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2ALDH1A1RAB9AMEN1 | |
| SCHEMBL4167930 | 0.74 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | claimed |
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | disclosed |