Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566316 | 1.00 | TRPV1 (0.46) | TRPV1MAPTKDM4ELMNATP53 | |
| SCHEMBL28565823 | 0.86 | MAPT (0.46) | TRPV1MAPTKDM4ELMNATP53 | |
| SCHEMBL28571346 | 0.84 | TBXAS1 (0.47) | LMNAMEN1POLBKMT2ATBXAS1 | |
| SCHEMBL30566315 | 0.84 | CYP19A1 (0.50) | TRPV1MAPTKDM4ELMNATP53 | |
| SCHEMBL30566320 | 0.84 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1ALOX15TBXAS1 | |
| SCHEMBL28566380 | 0.84 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1ALOX15TBXAS1 | |
| SCHEMBL28571445 | 0.84 | CYP19A1 (0.50) | TRPV1MAPTKDM4ELMNATP53 | |
| SCHEMBL28433866 | 0.78 | ALDH1A1 (0.51) | LMNAALDH1A1MEN1KMT2ATBXAS1 | |
| SCHEMBL28433865 | 0.78 | ALDH1A1 (0.51) | LMNAALDH1A1MEN1KMT2ATBXAS1 | |
| SCHEMBL28569168 | 0.77 | HDAC8 (0.45) | MAPTKDM4ESMN1; SMN2ALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | claimed |
| CN-112142673-B | Aryl alkene azole derivative and preparation method and application thereof | 聊城大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | disclosed |