Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167921 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTTRPM8KDM4EHPGD | |
| SCHEMBL13802873 | 0.90 | ALDH1A1 (0.53) | SMN1; SMN2MAPTTRPM8KDM4EHPGD | |
| SCHEMBL13802871 | 0.90 | KDM4E (0.53) | SMN1; SMN2MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL13802870 | 0.90 | KDM4E (0.54) | SMN1; SMN2MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL5223254 | 0.89 | MAPT (0.61) | SMN1; SMN2MAPTTRPM8KDM4EHPGD | |
| SCHEMBL14131559 | 0.89 | MAPT (0.61) | SMN1; SMN2MAPTTRPM8KDM4EHPGD | |
| SCHEMBL13802869 | 0.87 | KDM4E (0.52) | SMN1; SMN2MAPTTRPM8KDM4EHPGD | |
| SCHEMBL13802874 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTTRPM8KDM4EHPGD | |
| SCHEMBL13802890 | 0.81 | MAPT (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1POLB | |
| SCHEMBL13802856 | 0.80 | MAPT (0.55) | SMN1; SMN2MAPTKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149528-A1 | Cinnamic acid amides | BAYER HEALTHCARE AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-7402683-B2 | 3-(1,3-benzodioxol-5-yl)-N-{(1S)-3-[((1S)-2-methyl-1-{[(3R,4S)-4-methyl-2,5-dioxo-3-pyrrolidinyl]carbonyl}propyl)amino]-3-oxo-1-phenylpropyl}-2-propenamide; bactericide, bacterial infection; septic infections, bone and joint infections, skin infections; veterinary medicine | BAYER HEALTHCARE AG (DE) | 2008-07-22 | — | — | US | disclosed |
| US-20060178369-A1 | Cinnamic acid amides | INTERMED DISCOVERY GMBH (DE) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178369-A1 | Cinnamic acid amides | PIGS, NISCH, PIGO | SMN1; SMN2 2623/4885MAPT 2050/4885TRPM8 2857/4885 |
| US-20090149528-A1 | Cinnamic acid amides | PIGS, NISCH, PIGO | SMN1; SMN2 2623/4885MAPT 2050/4885TRPM8 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.