SCHEMBL28566015

SCHEMBL28566015

CCCCCCCCCCCCCCCCC1CC[Si](C)(C)[Si](C)(C)O1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 3/20 0.41
PPARG P37231 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
RAD52 P43351 1/20 0.33
GRM2 Q14416 6/20 0.31
SPHK2 Q9NRA0 3/20 0.30
SPHK1 Q9NYA1 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559866 1.00 EPHX1 (0.48) EPHX1ALDH1A1CYP1A2PPARGTDP1
SCHEMBL21646163 1.00 EPHX1 (0.48) EPHX1ALDH1A1CYP1A2PPARGTDP1
SCHEMBL28255120 1.00 EPHX1 (0.48) EPHX1ALDH1A1CYP1A2PPARGTDP1
SCHEMBL4759411 0.93 EPHX1 (0.38) EPHX1ALDH1A1CYP1A2
SCHEMBL29113010 0.86 SIGMAR1 (0.37) EPHX1ALDH1A1
SCHEMBL3631531 0.85
SCHEMBL28984865 0.84 EPHX1 (0.32) EPHX1
SCHEMBL28882490 0.84 ALDH1A1 (0.44) EPHX1ALDH1A1
SCHEMBL1011891 0.84 SIGMAR1 (0.34)
Ammonia Solution, Strong SCHEMBL28300543 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466935-B Synthesis process of silicon-hydrogen-containing cyclosiloxane 山东东岳有机硅材料股份有限公司 2024-04-16 CN disclosed
CN-117466935-A Synthesis process of silicon-hydrogen-containing cyclosiloxane 山东东岳有机硅材料股份有限公司 2024-01-30 CN disclosed
CN-112761022-B Ultra-light peeling force organic silicon release agent and preparation method and application thereof 广东标美硅氟新材料有限公司 2022-09-09 CN disclosed
CN-112745505-B Alkyl modified MDQ type silicon resin and preparation method and application thereof 广东标美硅氟新材料有限公司 2022-05-03 CN disclosed
CN-112761022-A Ultra-light peeling force organic silicon release agent and preparation method and application thereof 广东标美硅氟新材料有限公司 2021-05-07 CN disclosed
CN-112745505-A Alkyl modified MDQ type silicon resin and preparation method and application thereof 广东标美硅氟新材料有限公司 2021-05-04 CN disclosed