Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571865 | 0.88 | PRMT5 (0.39) | CYP2C9CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL28568806 | 0.88 | PIK3CD (0.35) | ALDH1A1KMT2AMEN1KDM4ENPC1 | |
| SCHEMBL28566103 | 0.85 | KMT2A (0.39) | CYP2C9CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL28334819 | 0.84 | LMNA (0.36) | KMT2AFAAHLMNAMAPK1VNN1 | |
| SCHEMBL28562358 | 0.84 | LMNA (0.36) | KMT2AFAAHLMNAMAPK1VNN1 | |
| SCHEMBL28565963 | 0.83 | LMNA (0.36) | KMT2AFAAHLMNAMAPK1VNN1 | |
| SCHEMBL28334820 | 0.78 | ITGAV (0.44) | KMT2AMEN1KDM4ELMNAMAPK1 | |
| SCHEMBL28565965 | 0.77 | ITGAV (0.43) | KMT2AMEN1KDM4ELMNAMAPK1 | |
| SCHEMBL28562872 | 0.77 | PIK3CD (0.43) | — | |
| SCHEMBL28568808 | 0.77 | HCRTR1 (0.35) | KMT2ANPC1LMNAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805001-A | Inhibition of alpha v beta 6 integrins | 莫菲克医疗股份有限公司 | 2021-05-14 | — | — | CN | disclosed |