Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334819 | 0.99 | LMNA (0.36) | LMNAMAPK1PDE10AITGAVITGB6 | |
| SCHEMBL28562358 | 0.99 | LMNA (0.36) | LMNAMAPK1PDE10AITGAVITGB6 | |
| SCHEMBL28558968 | 0.87 | ITGAV (0.41) | PDE10AITGAVITGB6 | |
| SCHEMBL28565965 | 0.86 | ITGAV (0.43) | LMNAMAPK1ITGAVITGB6KMT2A | |
| SCHEMBL28912907 | 0.86 | ITGAV (0.42) | PDE10AITGAVITGB6 | |
| SCHEMBL28334820 | 0.85 | ITGAV (0.44) | LMNAMAPK1ITGAVITGB6KMT2A | |
| SCHEMBL28566100 | 0.83 | CYP2C9 (0.37) | LMNAMAPK1KMT2AVNN1FAAH | |
| SCHEMBL28568806 | 0.82 | PIK3CD (0.35) | LMNAMAPK1KMT2A | |
| SCHEMBL28566103 | 0.77 | KMT2A (0.39) | LMNAMAPK1ITGAVITGB6KMT2A | |
| SCHEMBL28562405 | 0.77 | FAAH (0.37) | LMNAPDE10AITGAVFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805001-A | Inhibition of alpha v beta 6 integrins | 莫菲克医疗股份有限公司 | 2021-05-14 | — | — | CN | disclosed |