Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772321 | 0.81 | MEN1 (0.53) | POLBLMNARAB9AMEN1KMT2A | |
| SCHEMBL16397403 | 0.81 | MEN1 (0.53) | POLBLMNARAB9AMEN1KMT2A | |
| SCHEMBL11066401 | 0.80 | ALDH1A1 (0.49) | POLBLMNARAB9AMEN1KMT2A | |
| SCHEMBL22864579 | 0.80 | LMNA (0.58) | LMNARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL2070727 | 0.78 | GSK3B (0.38) | POLBRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9452430 | 0.76 | LMNA (0.46) | POLBLMNARAB9AMEN1KMT2A | |
| SCHEMBL11073849 | 0.75 | SMN1; SMN2 (0.54) | POLBLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL909726 | 0.75 | HDAC3 (0.58) | POLBLMNARAB9AMEN1KMT2A | |
| SCHEMBL24197589 | 0.73 | LMNA (0.50) | POLBLMNARAB9AMEN1KMT2A | |
| SCHEMBL4111270 | 0.73 | ALDH1A1 (0.70) | RAB9AMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098822-B | Preparation method for pranlukast key intermediate 3-amino-2-hydroxyacetophenone | 上海微巨实业有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-107098822-B | Preparation method for pranlukast key intermediate 3-amino-2-hydroxyacetophenone | 上海微巨实业有限公司 | 2021-05-28 | — | — | CN | disclosed |