Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.52 |
| ▸ | CYCS | P99999 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796561 | 0.95 | ENPP2 (0.55) | TOP1CYCSENPP2NPBWR1MAPT | |
| SCHEMBL29400418 | 0.95 | ENPP2 (0.55) | TOP1CYCSENPP2NPBWR1MAPT | |
| SCHEMBL29402717 | 0.94 | ENPP2 (0.53) | TOP1CYCSENPP2NPBWR1MAPT | |
| SCHEMBL29403163 | 0.94 | ENPP2 (0.53) | TOP1CYCSENPP2NPBWR1MAPT | |
| SCHEMBL10587131 | 0.94 | TOP1 (0.55) | TOP1CYCSENPP2FASNCYP19A1 | |
| SCHEMBL31154457 | 0.94 | TOP1 (0.55) | TOP1CYCSENPP2FASNCYP19A1 | |
| SCHEMBL30556440 | 0.94 | TOP1 (0.55) | TOP1CYCSENPP2FASNCYP19A1 | |
| SCHEMBL15134783 | 0.94 | TOP1 (0.55) | TOP1CYCSENPP2FASNCYP19A1 | |
| SCHEMBL8355904 | 0.94 | TOP1 (0.55) | TOP1CYCSENPP2FASNCYP19A1 | |
| SCHEMBL15134782 | 0.94 | TOP1 (0.55) | TOP1CYCSENPP2FASNCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047234-B | Amino and hydroxyl substituted porphyrin fluorescent matrix and preparation method thereof | 湖南科技大学 | 2021-05-07 | — | — | CN | claimed |
| CN-108047234-B | Amino and hydroxyl substituted porphyrin fluorescent matrix and preparation method thereof | 湖南科技大学 | 2021-05-07 | — | — | CN | disclosed |