Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.55 |
| ▸ | CYCS | P99999 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31154457 | 1.00 | TOP1 (0.55) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL15134783 | 1.00 | TOP1 (0.55) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL30556440 | 1.00 | TOP1 (0.55) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL15134782 | 1.00 | TOP1 (0.55) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL8355904 | 1.00 | TOP1 (0.55) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL11327076 | 0.94 | ENPP2 (0.57) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL29405657 | 0.94 | ENPP2 (0.57) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL28565650 | 0.94 | TOP1 (0.56) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL28566539 | 0.94 | TOP1 (0.52) | TOP1CYCSCYP19A1ENPP2MMP2 | |
| SCHEMBL13249184 | 0.93 | CYCS (0.56) | TOP1CYCSCYP19A1ENPP2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1242584-A | — | — | None | — | — | JP | disclosed |
| US-8901292-B2 | Method of mass production of tetrakis(p-nitrophenyl)porphyrins | THE HONG KONG POLYTECHNIC UNIVERISTY (HK) | 2014-12-02 | — | — | US | disclosed |
| CN-103664966-A | Method for preparing asymmetric 5,15-bis(p-nitrophenyl)-10, 20-diphenyl porphyrin compound | UNIV BEIJING TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |
| CN-103664966-A | Method for preparing asymmetric 5,15-bis(p-nitrophenyl)-10, 20-diphenyl porphyrin compound | UNIV BEIJING TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |
| US-20130190486-A1 | Method Of Mass Production Of Tetrakis(P-Nitrophenyl)Porphyrins | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2013-07-25 | — | — | US | disclosed |
| JP-H01242584-A | AROMATIC DIAMINE | IMAI YOSHIO | 1989-09-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190486-A1 | Method Of Mass Production Of Tetrakis(P-Nitrophenyl)Porphyrins | NPEPPS, PPOX, PNN | TOP1 2556/4885CYCS 521/4885CYP19A1 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.