Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004782 | 0.80 | MAPK14 (0.47) | MGLLMRGPRX4 | |
| SCHEMBL28658231 | 0.80 | ESRRA (0.37) | GRM5MEN1NPC1RAB9AKMT2A | |
| SCHEMBL17014137 | 0.79 | RECQL (0.41) | MGLLMRGPRX4PLAUPLATRECQL | |
| SCHEMBL28588449 | 0.78 | LRRK2 (0.45) | MRGPRX4PLAUPLATMEN1KMT2A | |
| SCHEMBL31086622 | 0.77 | KMT2A (0.46) | MGLLGRM5MEN1NPC1RAB9A | |
| SCHEMBL17008483 | 0.77 | KMT2A (0.46) | MGLLGRM5MEN1NPC1RAB9A | |
| SCHEMBL17017625 | 0.75 | MAPK14 (0.46) | MRGPRX4 | |
| SCHEMBL29711834 | 0.75 | MAPK14 (0.46) | MRGPRX4 | |
| SCHEMBL18546338 | 0.75 | MRGPRX4 (0.44) | MGLLMRGPRX4RECQLMEN1NPC1 | |
| SCHEMBL28775209 | 0.75 | RECQL (0.53) | MRGPRX4RECQLLOXLOXL3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110522731-B | Aromatic heterocycles as anti-inflammatory compounds | 瑞斯比维特有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-113264921-A | Pyrazolyl-ureas as kinase inhibitors | 瑞斯比维特有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-106573914-B | Pyrazolyl-ureas as kinase inhibitors | 瑞斯比维特有限公司 | 2021-05-28 | — | — | CN | disclosed |