Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 4/20 | 0.35 |
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | TEK | Q02763 | 3/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928319 | 0.82 | KDR (0.40) | ESRRAKDRLMNANPC1TSHR | |
| SCHEMBL8509431 | 0.81 | TSHR (0.42) | ESRRAKDRLMNANPC1TSHR | |
| SCHEMBL535774 | 0.81 | IDO1 (0.44) | LMNAMAPTPDGFRAMEN1KMT2A | |
| SCHEMBL28663309 | 0.81 | MAPK14 (0.35) | KDR | |
| SCHEMBL15567351 | 0.80 | MAPT (0.37) | ESRRAKDRLMNAMAPTNPC1 | |
| SCHEMBL28566745 | 0.80 | MGLL (0.43) | LMNAMAPTNPC1RAB9AMEN1 | |
| SCHEMBL15485154 | 0.79 | MAPK14 (0.46) | KDRSIRT2SIRT1SIRT3MET | |
| SCHEMBL15880529 | 0.78 | MEN1 (0.52) | MEN1KMT2AGRM5 | |
| SCHEMBL9609810 | 0.78 | CYP1A2 (0.38) | ESRRALMNAMAPTPDGFRAPDGFRB | |
| SCHEMBL28756211 | 0.77 | PLAAT3 (0.39) | LMNAMAPTNPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717162-A | Urea derivatives as kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-109071505-B | Kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-16 | — | — | CN | disclosed |