Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 16/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253538 | 0.87 | ROCK1 (0.45) | PDE4BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28577984 | 0.86 | MEN1 (0.45) | GRM5ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28573108 | 0.82 | MAPT (0.40) | GRM5ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28567363 | 0.80 | ALDH1A1 (0.56) | PDE4BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28252766 | 0.80 | NR1H4 (0.46) | PDE4BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28567263 | 0.80 | MAPT (0.56) | PDE4BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28866091 | 0.80 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28573112 | 0.75 | HDAC1 (0.46) | GRM5 | |
| SCHEMBL28570315 | 0.75 | MAPT (0.44) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28571810 | 0.73 | KMT2A (0.45) | ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794460-B | 1,2, 4-oxadiazole-3, 4-dihydroquinoline compound and preparation method and application thereof | 贵州医科大学 | 2021-05-28 | — | — | CN | disclosed |