Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 3/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172719 | 0.94 | PIM1 (0.49) | HTTKDM4EMAP4K4F10ALDH1A1 | |
| SCHEMBL4445734 | 0.88 | MAP4K4 (0.53) | KDM4EMAP4K4F10AURKAPDPK1 | |
| SCHEMBL30172721 | 0.88 | ALDH1A1 (0.48) | HTTKDM4EALDH1A1GAAKDM4D | |
| SCHEMBL4443681 | 0.88 | ALDH1A1 (0.48) | HTTKDM4EALDH1A1GAAKDM4D | |
| SCHEMBL28567290 | 0.88 | MAP4K4 (0.51) | KDM4EMAP4K4F10AURKAPDPK1 | |
| SCHEMBL4439875 | 0.88 | MAP4K4 (0.51) | KDM4EMAP4K4F10AURKAPDPK1 | |
| SCHEMBL4436879 | 0.88 | MAP4K4 (0.52) | HTTKDM4EMAP4K4F10AURKA | |
| SCHEMBL4439169 | 0.87 | MAP4K4 (0.52) | KDM4EMAP4K4F10AURKAPDPK1 | |
| SCHEMBL807386 | 0.87 | MAP4K4 (0.52) | KDM4EMAP4K4F10AURKAPDPK1 | |
| SCHEMBL28572991 | 0.87 | MAP4K4 (0.52) | KDM4EMAP4K4F10AURKAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |