Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566910 | 1.00 | BRD4 (0.57) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL11622652 | 0.87 | MAPT (0.66) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL12667143 | 0.87 | MAPT (0.66) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL5011683 | 0.86 | BRD4 (0.55) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL563682 | 0.86 | BRD4 (0.55) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL20676016 | 0.83 | MAPT (0.77) | MAPTSMN1; SMN2KMT2AGAAPOLB | |
| SCHEMBL12206410 | 0.82 | BRD4 (0.51) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL28561759 | 0.81 | BRD4 (0.50) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL28561762 | 0.81 | BRD4 (0.50) | BRD4MAPTSMN1; SMN2KMT2ACA1 | |
| SCHEMBL11997282 | 0.80 | TSHR (0.60) | BRD4MAPTSMN1; SMN2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903302-B | Preparation method of gamma-lactam bridged dipeptide compound | 韶远科技（上海)有限公司 | 2021-05-14 | — | — | CN | disclosed |