Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.51 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526545 | 0.88 | CDYL2 (0.52) | CDYL2CDYLEGFRGAAMAPT | |
| SCHEMBL7383444 | 0.86 | CDYL2 (0.54) | CDYL2CDYLGAAMAPTTP53 | |
| SCHEMBL28913497 | 0.84 | CDYL2 (0.54) | CDYL2CDYLEGFRGAAMAPT | |
| SCHEMBL8998987 | 0.80 | EGFR (0.72) | EGFRGAAMAPTHSD17B10HTT | |
| SCHEMBL14484996 | 0.77 | CDYL2 (0.58) | CDYL2CDYLEGFRMAPTTP53 | |
| SCHEMBL7385586 | 0.76 | CDYL2 (0.60) | CDYL2CDYLMAPTTP53KMT2A | |
| SCHEMBL1129626 | 0.76 | HTR7 (0.49) | CDYL2CDYLGAAMAPTTP53 | |
| SCHEMBL3201173 | 0.76 | EGFR (0.65) | EGFRGAAMAPTHSD17B10HTT | |
| SCHEMBL7382582 | 0.76 | CDYL2 (0.57) | CDYL2CDYLMAPTTP53KMT2A | |
| SCHEMBL7072903 | 0.75 | USP2 (0.41) | GAATP53USP2KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863899-B | Synthetic method and application of indoline-2-ketone compound | 中国科学院兰州化学物理研究所 | 2021-05-28 | — | — | CN | disclosed |