SCHEMBL28567265

SCHEMBL28567265

COC(OC)(C(=O)c1ccccc1C)c1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.42
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
CTNNB1 P35222 1/20 0.40
WNT3A P56704 1/20 0.40
HPGD P15428 1/20 0.39
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.38
ERCC5 P28715 1/20 0.38
FEN1 P39748 1/20 0.38
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KCNK3 O14649 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17395169 0.83 CTNNB1 (0.38) NPC1RAB9ACTNNB1WNT3AHPGD
SCHEMBL28000178 0.78 NPC1 (0.44) CES1NPC1RAB9AHPGDERCC5
SCHEMBL11259732 0.77 ADRB2 (0.43) NPC1RAB9AHPGDALDH1A1ERCC5
SCHEMBL7949878 0.71 HPGD (0.47) HPGDALDH1A1ERCC5FEN1THRB
SCHEMBL5096830 0.70 HPGD (0.46) NPC1RAB9AHPGDERCC5FEN1
SCHEMBL8914360 0.70 HPGD (0.46) HPGDALDH1A1ERCC5FEN1THRB
SCHEMBL29645048 0.70 CES1 (0.50) CES1HPGDALDH1A1ERCC5FEN1
SCHEMBL1199962 0.70 CES1 (0.50) CES1HPGDALDH1A1ERCC5FEN1
SCHEMBL19278858 0.70 HPGD (0.46) HPGDALDH1A1ERCC5FEN1SMN1; SMN2
SCHEMBL10455866 0.70 HPGD (0.46) NPC1RAB9AHPGDALDH1A1ERCC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265328-B Method for green synthesis of benzoin diether driven by visible light 兰州大学 2021-06-04 CN disclosed