Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854295 | 0.91 | MAPK14 (0.68) | ALDH1A1MAPK14MAPK1NPC1RAB9A | |
| SCHEMBL14097124 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MAPK14MAPK1NPC1RAB9A | |
| SCHEMBL14097125 | 0.87 | ALDH1A1 (0.67) | ALDH1A1MAPK14MAPK1PKMPOLB | |
| SCHEMBL2856945 | 0.85 | ALDH1A1 (0.81) | ALDH1A1MAPK14MAPK1NPC1RAB9A | |
| SCHEMBL14097121 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPK14MAPK1PKMPOLB | |
| SCHEMBL2857605 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK14MAPK1POLBMAPT | |
| SCHEMBL14097122 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPK14MAPK1NPC1RAB9A | |
| SCHEMBL2852492 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK14MAPK1NPC1RAB9A | |
| SCHEMBL14097123 | 0.81 | MAPT (0.78) | ALDH1A1MAPK14MAPK1NPC1RAB9A | |
| SCHEMBL14097120 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPK14MAPK1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |