Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856274 | 0.92 | MAPT (0.49) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2860824 | 0.88 | LMNA (0.57) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2854755 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2856997 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2853459 | 0.85 | MAPT (0.52) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2857472 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2859086 | 0.85 | LMNA (0.48) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2856275 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1RAB9APKMMAPT | |
| SCHEMBL2850383 | 0.83 | KMT2A (0.47) | ALDH1A1MAPK14MAPK1RAB9APKM | |
| SCHEMBL2861640 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK14MAPK1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |