Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | MGAM | O43451 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558217 | 0.86 | KMT2A (0.55) | KMT2AMEN1MGAMKDM4EMAPT | |
| SCHEMBL27963004 | 0.85 | HDAC3 (0.61) | KMT2AMEN1MGAMKDM4EMAPT | |
| SCHEMBL30607054 | 0.85 | HDAC3 (0.61) | KMT2AMEN1MGAMKDM4EMAPT | |
| SCHEMBL28556004 | 0.84 | KMT2A (0.53) | KMT2AMEN1MGAMKDM4EMAPT | |
| SCHEMBL27917533 | 0.84 | MEN1 (0.74) | KMT2AMEN1MGAM | |
| Harman-3-Carboxylic Acid SCHEMBL3967948 | 0.82 | MAPT (0.73) | KMT2AMEN1KDM4EMAPTLMNA | |
| SCHEMBL30607047 | 0.82 | HDAC1 (0.53) | KMT2AMEN1MGAMKDM4EMAPT | |
| SCHEMBL2216422 | 0.80 | MEN1 (0.65) | KMT2AMEN1MGAMPOLBMITF | |
| SCHEMBL30607046 | 0.79 | MGAM (0.57) | KMT2AMEN1MGAMKDM4EMAPT | |
| SCHEMBL29817694 | 0.79 | MEN1 (0.63) | KMT2AMEN1MGAMPOLBMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134460-B | Synthesis method of beta-carboline compound | 南开大学 | 2021-04-06 | — | — | CN | disclosed |